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The term __________ refers to the degree or intensity of pathogenicity.

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Listeria monocytogenes propels itself through mammalian host cells using


A) a modified form of gliding motility.
B) host cell actin and other cytoskeletal proteins.
C) periplasmic flagella.
D) fimbriae-based twitching motility.

E) None of the above
F) All of the above

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B

Macrophages are phagocytic cells.

A) True
B) False

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Which of the following must a pathogen possess in order for it to be successful at causing infectious disease?


A) Ability to be transported initially to the host
B) Ability to exit the host
C) Ability to adhere to,colonize,or invade the host
D) Ability to damage the host
E) All of the choices are correct.

F) A) and E)
G) A) and B)

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An animal that is infected with a parasitic organism that can also infect humans is called a(n) ________ host.


A) reservoir
B) endoparasitic
C) transfer
D) intermediate

E) A) and B)
F) All of the above

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Bacteria within biofilms exchange


A) plasmids.
B) quorum-sensing molecules.
C) nutrients.
D) All of the choices are correct.

E) A) and B)
F) None of the above

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The term "sexually transmitted infection" is more accurate than "sexually transmitted disease" because it is a sexually transmitted pathogen may colonize host tissues without causing further damage to the host.

A) True
B) False

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Endotoxins include which of the following?


A) Diphtheria toxin
B) Lipopolysaccharide
C) Tetanus toxin
D) Botulinum toxin

E) None of the above
F) C) and D)

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Many bacteria are pathogenic because they carry large segments of DNA called __________ _________,which were acquired by horizontal gene transfer,and which carry genes responsible for virulence.

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pathogenic...

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Virulence may be measured experimentally at the host level by the __________ __________ __________,which measures the number of pathogens that kills 50% of an experimental group of hosts within a specified amount of time.

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Because LPS is bound to the surface of bacteria,it is called a(n)__________.

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The final outcome of most host-parasite relationships depends on


A) the number of organisms present in or on the host.
B) the virulence of the organism.
C) the host's defenses.
D) All of the choices are correct.

E) A) and B)
F) A) and D)

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A person who is infected with a potential pathogen fails to develop signs or symptoms of disease.This correlates with initial microbial dose, microbial lethality,and/or replication rate of the pathogen.


A) low; high; low
B) low; low; high
C) high; low; low
D) high; low; high

E) A) and B)
F) B) and C)

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The only organisms to produce endotoxins are Gram-negative bacteria.

A) True
B) False

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Pathogenicity islands are typically associated with


A) genes encoding tRNA.
B) genes encoding rRNA.
C) G+C content similar to the rest of the bacterial genome.
D) None of the choices are correct.

E) A) and B)
F) A) and C)

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Which of the following is a facultative,rather than obligate,intracellular pathogen?


A) Chlamydia
B) Brucella
C) Rickettsia
D) All of the choices are correct.

E) None of the above
F) C) and D)

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Endotoxin is released when


A) Gram-negative pathogens lyse or divide.
B) cells are starved for iron.
C) cells are lysogenic for the beta phage.
D) All of the choices are correct.

E) C) and D)
F) A) and C)

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A

Exotoxins can be denatured by iodine to form __________,which are useful in vaccines.

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toxoids

A patient develops a high fever due to a Gram-negative pathogen.Which of the following is a certain mediator of illness in this case?


A) Endotoxin
B) Exotoxin
C) Both endotoxin and exotoxin
D) Neither endotoxin nor exotoxin

E) A) and D)
F) B) and C)

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Fever response can be triggered by an endogenous pyrogen called interleukin-1.

A) True
B) False

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