Question 1

Cell bodies of serotonin neurons are located within the

Accepted Answer

A)   substantia nigra.
B)   basal forebrain.
C)   ventral tegmental area.
D)   spinal cord.
E)   raphe nuclei.F) A) and C)
G) B) and D)

Question 2

________ refers to the process by which drugs are absorbed, distributed within the body, metabolized, and then excreted from the body.

Accepted Answer

A)   Pharmacotherapy
B)   Pharmacokinetics
C)   Drug metabolism
D)   Pharmacodynamics
E)   NeurobotanyF) D) and E)
G) A) and E)

Question 3

The drug reserpine

Accepted Answer

A)   was used medically to treat high blood pressure.
B)   is used to treat myasthenia gravis.
C)   blocks the storage of monoamines in vesicles.
D)   can produce Parkinson's disease in some persons.
E)   interferes with the synthesis of dopamine.F) A) and C)
G) B) and D)

Question 4

Degeneration of neurons within the ________ dopamine system leads to Parkinson's disease.

Accepted Answer

A)   nigrostriatal
B)   mesocortical
C)   hypothalamocortical
D)   mesolimbic
E)   retinal-suprachiasmaticF) B) and E)
G) B) and D)

Question 5

The disease process of myasthenia gravis produces muscle weakness by

Accepted Answer

A)   overproducing ACh receptors on muscles.
B)   reducing ACh function in the basal forebrain.
C)   reducing the number of ACh receptors on muscles.
D)   reducing ACh function in the dorsolateral pons.
E)   enhancing the release of glycine onto spinal cord motoneurons.F) A) and B)
G) C) and D)

Question 6

The ________ route of drug administration is commonly used for small laboratory animals such as the rat.

Accepted Answer

A)   intraperitoneal
B)   oral
C)   intravascular
D)   topical
E)   intranasalF) C) and D)
G) A) and B)

Question 7

Drugs that block the reuptake of serotonin or that cause the release of serotonin are used therapeutically to treat

Accepted Answer

A)   anorexia nervosa.
B)   depression.
C)   mania.
D)   psychosis.
E)   bipolar disorder.F) A) and C)
G) A) and B)

Question 8

Which pair below represents the receptor subtypes for acetylcholine?

Accepted Answer

A)   cholinergic; adrenergic
B)   muscarinic; adrenergic
C)   alpha-cholinergic; beta-cholinergic
D)   nicotinic; muscarinic
E)   beta-cholinergic; delta-cholinergicF) A) and E)
G) C) and D)

Question 9

Damage to the ________ cholinergic system would be expected to impair learning.

Accepted Answer

A)   dorsolateral pons
B)   hypothalamocortical
C)   basal forebrain
D)   medial septal
E)   corticospinalF) B) and C)
G) B) and E)

Question 10

Which pair of drugs below is known to facilitate and inhibit (respectively)  the release of acetylcholine?

Accepted Answer

A)   fluoxetine; nicotine
B)   botulinum toxin; muscarine
C)   botulinum toxin; black widow spider venom
D)   black widow spider venom; botulinum toxin
E)   black widow spider venom; fluoxetineF) A) and E)
G) A) and C)

Question 11

The major excitatory neurotransmitter in the brain is a(n)  ____________ called _______________.

Accepted Answer

A)   amino acid; acetylcholine
B)   amino acid; glutamate
C)   monamine; serotonin
D)   monoamine; dopamine
E)   amino acid; dopamineF) B) and D)
G) B) and E)

Question 12

Damage to the ________ dopaminergic system would be expected to impair movement.

Accepted Answer

A)   nigrostriatal
B)   hypothalamocortical
C)   mesocortical
D)   mesolimbic
E)   corticospinalF) A) and B)
G) A) and C)

Question 13

Where a drug acts in the cell would be a

Accepted Answer

A)   site of action.
B)   drug effect.
C)   exogenous substance.
D)   endogenous substance.
E)   drug.F) B) and C)
G) A) and C)

Question 14

________ demonstrate the effect of a particular dose until the maximum effect is reached.

Accepted Answer

Dose respo...

Question 15

Hemicholnium-3 blocks the choline transporter, preventing recycling of choline. This drug is a(n)

Accepted Answer

A)   agonist.
B)   promotor.
C)   villain.
D)   antagonist.
E)   precursor.F) A) and B)
G) B) and D)

Question 16

A drug that binds with a postsynaptic receptor, but does not open ion channels, would be termed a(n)

Accepted Answer

A)   direct agonist.
B)   ligand.
C)   direct synergist.
D)   direct antagonist.
E)   indirect antagonistF) A) and B)
G) D) and E)

Question 17

Glutamate, GABA, and glycine are important because these are

Accepted Answer

A)   the major excitatory neurotransmitters in the CNS.
B)   known to be solely inhibitory in the brain.
C)   the predominant neuromodulators in the spinal cord.
D)   the most common neurotransmitters in the CNS.
E)   involved in Parkinson's disease.F) B) and C)
G) C) and D)

Question 18

Alcohol withdrawal can lead to seizures because of the effect of alcohol on

Accepted Answer

A)   blocking AMPA receptors.
B)   stimulating 5-HT receptors.
C)   displacing magnesium ions from the GABA receptors.
D)   blocking NMDA receptors.
E)   blocking 5-HT receptors.F) C) and D)
G) B) and C)

Question 19

Describe the biosynthesis of acetylcholine. List three different means that would act to alter the release of acetylcholine.

Accepted Answer

ACh is formed from choline and acetyl-co...

Question 20

Serotonin is synthesized from

Accepted Answer

A)   tyrosine.
B)   tyramine.
C)   tryptophan.
D)   blood platelets.
E)   glutamate.F) A) and D)
G) B) and C)

Exam 4: Psychopharmacology

Describe the biosynthesis of acetylcholine. List three different means that would act to alter the release of acetylcholine.

Correct AnswerverifiedACh is formed from choline and acetyl-co...View AnswerShow Answer

The major excitatory neurotransmitter in the brain is a(n) ____________ called _______________.

Correct AnswerverifiedShow Answer

Degeneration of neurons within the ________ dopamine system leads to Parkinson's disease.

Correct AnswerverifiedShow Answer

Damage to the ________ cholinergic system would be expected to impair learning.

Correct AnswerverifiedShow Answer

________ refers to the process by which drugs are absorbed, distributed within the body, metabolized, and then excreted from the body.

Correct AnswerverifiedShow Answer

Drugs that block the reuptake of serotonin or that cause the release of serotonin are used therapeutically to treat

Correct AnswerverifiedShow Answer

Where a drug acts in the cell would be a

Correct AnswerverifiedShow Answer

Cell bodies of serotonin neurons are located within the

Correct AnswerverifiedShow Answer

Alcohol withdrawal can lead to seizures because of the effect of alcohol on

Correct AnswerverifiedShow Answer

The drug reserpine

Correct AnswerverifiedShow Answer

A drug that binds with a postsynaptic receptor, but does not open ion channels, would be termed a(n)

Correct AnswerverifiedShow Answer

Which pair below represents the receptor subtypes for acetylcholine?

Correct AnswerverifiedShow Answer

The disease process of myasthenia gravis produces muscle weakness by

Correct AnswerverifiedShow Answer

The ________ route of drug administration is commonly used for small laboratory animals such as the rat.

Correct AnswerverifiedShow Answer

Glutamate, GABA, and glycine are important because these are

Correct AnswerverifiedShow Answer

________ demonstrate the effect of a particular dose until the maximum effect is reached.

Correct AnswerverifiedDose respo...View AnswerShow Answer

Which pair of drugs below is known to facilitate and inhibit (respectively) the release of acetylcholine?

Correct AnswerverifiedShow Answer

Damage to the ________ dopaminergic system would be expected to impair movement.

Correct AnswerverifiedShow Answer

Serotonin is synthesized from

Correct AnswerverifiedShow Answer

Hemicholnium-3 blocks the choline transporter, preventing recycling of choline. This drug is a(n)

Correct AnswerverifiedShow Answer

Correct Answer
verified
ACh is formed from choline and acetyl-co...
View Answer

The major excitatory neurotransmitter in the brain is a(n) called ___.

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
Dose respo...
View Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified